Managing Treatment Experience Study

Making methotrexate easier to understand—with children, for children

Welcome to the MTX Study

Empowering children to feel confident and informed about methotrexate

The Managing Treatment eXperience (MTX) study is a new research project funded by the National Institute for Health and Care Research (NIHR), focused on improving how children with rheumatic conditions understand and manage their treatment with methotrexate.

Methotrexate is a common medication for children and young people to take for rheumatic conditions. Children, families, and healthcare professionals have told us that better, more child-friendly information is urgently needed. That’s where this project comes in.

Over the next 18 months, our team will work closely with children aged 6–16, their families, and clinicians to co-create engaging resources—like animations, activity books, and prompt cards—that make methotrexate treatment easier to understand and manage.

This study is led by a passionate team : Dr Daniela Ghio, Professor Lucy Bray, Mrs Emily Earle, Dr Hanna Lythgoe, Dr Clare Pain, Mr Octavio Aragon Cuevas, and Ms Sarah Aitken.

Together, we’re committed to listening to children’s voices and creating tools that truly support them on their treatment journey.

Learn more about the project, meet the team, and find out how to get involved.

Supporting Children with Arthritis – CCAA

The CCAA is a UK charity that supports children and young people living with arthritis, along with their families. CCAA offers guidance, peer support, and educational resources to help families navigate the challenges of arthritis. They also run events and workshops that connect families and empower young people to live confidently with their condition.

CCAA is here for families living with Arthritis — offering friendly support, empowering workshops, and events that bring people together. Whether you're newly diagnosed or looking to connect, CCAA helps children and families feel informed, supported, and less alone.

👉 Learn more at www.ccaa.org.uk

CCAA Website